Hayles has recovered from illiness, and Hopkinson returns after serving his suspension. Marcus Martin, who suffered a dead leg during Truro's dramatic 2-2 draw against Dorchester last week, is also fit to play.
Their oppoenents Welling sit three points behind league leaders Salisbury City at the top of the Blue Square Bet Conference South, and Hodges said he expected yet another difficult afternoon for his side.
"There's no doubt this is going to be a really tough match," he said.
"The view of several managers I've spoken to is that this is the team to beat this season; they're probably going to win the league. But we'll give it our very best shot, as this squad always does."