The devon outfit may well have topped the list of teams Town managers Robbie Stephens and Les Gilbert wanted to avoid on the opening day, with Parkway once again expected to challenge for the league title having made some big-name signings during the summer.
And it doesn't let up for Falmouth. Three days later they entertain Newquay, now managed by former Town boss Alan Carey.
The following weekend sees the divison one west season get underway.
Last season's runners up and beaten Senior Cup finalists Helston Athletic kick off their 2013-14 campaign at home against Truro City Reserves. Penryn Athletic, themselves Senior Cup semi-finalists, make the trip to Callington Town, and Dennis Annear's Porthleven visit Hayle.
Full opening day premier division fixtures are as follows:
Camelford v Elburton Villa
Cullompton Rangers v Ivybridge Town
Elmore v Launceston
Falmouth Town v Plymouth Parkway
Godolphin Atlantic v St Austell
Liskeard Athletic v Newquay
Saltash United v St.Blazey
Tavistock v Exmouth Town
Bodmin Town v Witheridge
Division one west (Saturday, August 17):
Bude v Vospers Oak Villa
Callington Town v Penryn Athletic
Hayle v Porthleven
Helston Athletic v Truro City
Holsworthy v Dobwalls
Mousehole v St Dennis
Penzance v Perranporth
Wadebridge Town v Sticker